HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methoxyacetyl chloride → 11beta,17-Dihydroxy-21-methoxyacetoxy-6alpha-methyl-4-pregnene-3,20-dione
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methoxyacetyl chloride | HCID 96623 | — |
| Reactant | 6alpha-Methylhydrocortisone | HCID 102147 | — |
| Product | 11beta,17-Dihydroxy-21-methoxyacetoxy-6alpha-methyl-4-pregnene-3,20-dione | HCID 70501795 | — |
Reaction Steps
1.5 g of 11β,17,21-trihydroxy-6α-methyl-4-pregnene-3,20-dione is reacted analogously to Example 1(a) with methoxyacetic acid chloride, worked up, and chromatographed, thus isolating 1.6 g of 11β,17-dihydroxy-21-methoxyacetoxy-6α-methyl-4-pregnene-3,20-dione.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04435390 |
| Source dataset | uspto-grants-1984_03 |
| ORD ID | ord-e65678ce00d24710ad0a1e0b2007dc3d |
| Source note | uspto-grants-1984_03 |