HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Carbonate → HCID 20468252, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Carbonate | HCID 10340 | — |
| Reactant | 1-Iodopropane | HCID 33643 | — |
| Reactant | HCID 15614163 | HCID 15614163 | — |
| Product | HCID 20468252 | HCID 20468252 | — |
Reaction Steps
1,3-dihydro-4-(piperidin-3-yl)-2H-indole-2-one and n-propyl iodide in dimethylformaimide were reacted in the presence of sodium carbonate to obtain 1,3-dihydro-4-(1-propyl-piperidin-3-yl)-2H-indole-2-one. A solution of the latter in ether was admixed with an ether solution saturated with hydrogen chloride and the recovered product after crystallization from an isopropanol-methanol mixture melted at 260° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04435408 |
| Source dataset | uspto-grants-1984_03 |
| ORD ID | ord-0aefc65851fe4af2ad3d9ceeccb29dc6 |
| Source note | uspto-grants-1984_03 |