Hydrochloric Acid → HCID 23313793, compound

HRID 1903162Notes

Reaction equation

HRID 1903162 reaction equation
N([N:5]1[C:13]2[C:8](=[CH:9][C:10]([NH:17]C(C)=O)=[C:11]([N+:14]([O-:16])=[O:15])[CH:12]=2)[CH2:7][CH2:6]1)C(C)=O.[ClH:21]>CO>[ClH:21].[NH2:17][C:10]1[CH:9]=[C:8]2[C:13](=[CH:12][C:11]=1[N+:14]([O-:16])=[O:15])[NH:5][CH2:6][CH2:7]2

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 57033336HCID 57033336, compound

Product 1

HCID 23313793HCID 23313793, compoundYield 82.5%

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent2×

Procedure

21.4 g of 1,5-diacetamino-6-nitro-indoline were dissolved in 2.5 l of methanol, boiled under reflux overnight with 750 ml of 4 N hydrochloric acid in methanol and then evaporated. There were obtained 14.2 g (82.5% of theory) of 5-amino-6-nitro-indoline hydrochloride of melting point 259° C.

Workup

  1. customevaporated

Sources & evidence

ORD record
ord-eb3370c1b93c40f0b0857897defcfb7d
Source dataset
uspto-grants-1984_03
Patent number
US04435406

Reaction notes

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