HuagongsheHuagongshe Chemistry Print Report · For research reference only
Trifluoroacetic acid → HCID 13300632, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Trifluoroacetic acid | HCID 6422 | — |
| Reactant | Sodium borohydride | HCID 4311764 | — |
| Reactant | HCID 13300597 | HCID 13300597 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 13300632 | HCID 13300632 | — |
Reaction Steps
To trifluoroacetic acid (120 ml.) under a nitrogen atmosphere were added sodium borohydride pellets (5.39 g.) over a period of 30 minutes at 5° C. A solution of ethyl 6,7-dichloro-2,3-dihydro-5-(p-hydroxybenzoyl)-benzofuran-2-carboxylate (7.35 g.) in methylene chloride (50 ml.) was then added dropwise over 30 minutes, and the mixture stirred at room temperature for 22 hours.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04435422 |
| Source dataset | uspto-grants-1984_03 |
| ORD ID | ord-acb8a165402a412fb0c0f2bf95450dc1 |
| Source note | uspto-grants-1984_03 |