Hydrochloric Acid → HCID 70514933, compound

HRID 1903212Notes

Reaction equation

HRID 1903212 reaction equation
[NH2:1][CH2:2][C:3]1[CH:4]=[C:5]([CH:24]=[CH:25][C:26]=1[OH:27])[C:6]([C:8]1[C:9]([Cl:23])=[C:10]([Cl:22])[C:11]2[O:15][CH:14]([C:16]([O:18]CC)=[O:17])[CH2:13][C:12]=2[CH:21]=1)=[O:7].Cl>C(O)C>[ClH:22].[NH2:1][CH2:2][C:3]1[CH:4]=[C:5]([CH:24]=[CH:25][C:26]=1[OH:27])[C:6]([C:8]1[C:9]([Cl:23])=[C:10]([Cl:22])[C:11]2[O:15][CH:14]([C:16]([OH:18])=[O:17])[CH2:13][C:12]=2[CH:21]=1)=[O:7]

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 13300606HCID 13300606, compound

Product 1

HCID 70514933HCID 70514933, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

A sample of crude ethyl 5-(3-aminomethyl-4-hydroxybenzoyl)-6,7-dichloro-2,3-dihydrobenzofuran-2-carboxylate (600 mg.) was dissolved in 10 ml. of ethanol and treated with 4% aqueous HCl (125 ml.) for five hours at reflux.

Workup

  1. temperatureat reflux

Sources & evidence

ORD record
ord-f951b2c841de4278846e878ee906a850
Source dataset
uspto-grants-1984_03
Patent number
US04435422

Reaction notes

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