HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1903243Generated: October 30, 2026
HCID 13273322, compound → 2-(Difluoromethyl)hex-5-enoic acid
https://huagongshe.com/reaction/1903243
Participants
| Role | Name | HCID | Charge |
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| Reactant | HCID 13273322 | HCID 13273322 | — |
| Solvent | Acetic Acid | HCID 176 | — |
| Product | 2-(Difluoromethyl)hex-5-enoic acid | HCID 13273323 | 71% |
Reaction Steps
2-Carboxy 2-difluoromethyl 5-hexenoic acid, prepared as in Step C (1.040 g, 5 mM) is dissolved in glacial acetic acid (5 ml) and the mixture is heated at 110° C. for 16 hours. The solvent is evaporated in vacuo yielding a colorless oil. The acid is isolated by distillation under reduced pressure. 0.585 g (yield 71%). Bp: 67° C./0.01 mm Hg.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US04435425 |
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| Source dataset | uspto-grants-1984_03 |
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| ORD ID | ord-a910656b234743efa0dc2c514ab18484 |
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| Source note | uspto-grants-1984_03 |
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