Benzyl Bromide → HCID 13392732, compound

HRID 1903307Notes

Reaction equation

HRID 1903307 reaction equation
[CH3:1][N:2]([CH3:19])[C:3]1[N:4]=[C:5]([N:13]2[CH2:18][CH2:17][NH:16][CH2:15][CH2:14]2)[C:6]2[S:12][CH2:11][CH2:10][CH2:9][C:7]=2[N:8]=1.[CH2:20](Br)[C:21]1[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=1>>[CH2:20]([N:16]1[CH2:15][CH2:14][N:13]([C:5]2[C:6]3[S:12][CH2:11][CH2:10][CH2:9][C:7]=3[N:8]=[C:3]([N:2]([CH3:19])[CH3:1])[N:4]=2)[CH2:18][CH2:17]1)[C:21]1[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=1

Participants

3

Reactant 2

HCID 7498Benzyl BromideHCID 13307174HCID 13307174, compound

Product 1

HCID 13392732HCID 13392732, compound

Procedure

2-Dimethylamino-4-piperazino-7,8-dihydro-6H-thiopyrano[3,2-d]pyrimidine obtained in Example 11 was reacted with benzyl bromide in the same manner as described in Example 3 to obtain 4-(N-benzylpiperazino)-2-dimethylamino-7,8-dihydro-6H-thiopyrano[3,2-d]pyrimidine which was then recrystallized from dichloromethane-diethyl ether. Colorless prisms. Melting point: 106° to 108° C.

Sources & evidence

ORD record
ord-6a94765f6c374f7280e807c13864419b
Source dataset
uspto-grants-1984_03
Patent number
US04435566

Reaction notes

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