Ethylamine → HCID 13057017, compound

Participants

Reaction Steps

To 12 g of cooled liquid ethylamine in a small pressure bottle is added 2.8 g of t-boc-gly-4-F-phe OCH3, 6b, and the solution stirred overnight at room temperature. Evaporation of the solvent gives a solid, which when recrystallized from 95% ethanol yields 8b, m.p. 181°-182.5° C. Alternatively, 8b may be prepared from 7b, according to the procedure of Example 8a.

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