HRID1903548

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID6140

L-Phenylalanine

C9H11NO2

结构：CCCCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCCCCCC)CC(=O)NCC(=O)O

HCID20216775

N-[3-(Hexadecanoyloxy)octadecanoyl]glycine

C36H69NO5

PRODUCTS

生成物

结构：CCCCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCCCCCC)CC(=O)NCC(=O)N[C@@H](Cc1ccccc1)C(=O)O

HCID54114728

未命名化合物

收率 64.8%

PROCEDURE

实验过程

Starting from N-(3-hexadecanoyloxyoctadecanoyl)glycine (2.6 g) prepared by the method described in Example 27 and L-phenylalanine (1.65 g), N-[N-(3-hexadecanoyloxyoctadecanoyl)glycyl]-L-phenylalanine (2.1 g) was obtained as powders according to a similar manner to that of Example 29.

WORKUP

后处理

customprepared by the method

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-80dc53e49f054c9da5bde262f37aca5a
来源数据集: uspto-grants-1984_03
DOI: 10.6084/m9.figshare.5104873.v1
专利: US04436726
来源说明: uspto-grants-1984_03

反应 SMILES

[C:1]([O:18][CH:19]([CH2:28][CH2:29][CH2:30][CH2:31][CH2:32][CH2:33][CH2:34][CH2:35][CH2:36][CH2:37][CH2:38][CH2:39][CH2:40][CH2:41][CH3:42])[CH2:20][C:21]([NH:23][CH2:24][C:25]([OH:27])=O)=[O:22])(=[O:17])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH3:16].[NH2:43][C@H:44]([C:52]([OH:54])=[O:53])[CH2:45][C:46]1[CH:51]=[CH:50][CH:49]=[CH:48][CH:47]=1>>[C:1]([O:18][CH:19]([CH2:28][CH2:29][CH2:30][CH2:31][CH2:32][CH2:33][CH2:34][CH2:35][CH2:36][CH2:37][CH2:38][CH2:39][CH2:40][CH2:41][CH3:42])[CH2:20][C:21]([NH:23][CH2:24][C:25]([NH:43][C@H:44]([C:52]([OH:54])=[O:53])[CH2:45][C:46]1[CH:51]=[CH:50][CH:49]=[CH:48][CH:47]=1)=[O:27])=[O:22])(=[O:17])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH3:16]