HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Chloro-4,5-dihydroimidazole → HCID 13255561, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Chloro-4,5-dihydroimidazole | HCID 236236 | — |
| Reactant | 1-methyl-1H-indazol-5-amine | HCID 2768032 | — |
| Solvent | Diethyl Ether | HCID 3283 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | HCID 13255561 | HCID 13255561 | — |
Reaction Steps
5-amino-1-methyl-indazole is dissolved in absolute THF and treated with a solution of an equimolar quantity of 2-chloro-imidazoline in ether. The mixture is stirred for 48 hours in a darkened, sealed flask at room temperature. The precipitated reaction product is separated and recrystallized from ethanol. The purified, white, crystallized hydrochloride has a melting point from 240° to 241° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04436913 |
| Source dataset | uspto-grants-1984_03 |
| ORD ID | ord-038779f0258847959f2af2be5eaf2925 |
| Source note | uspto-grants-1984_03 |