Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | Cyclohexyl isocyanate | HCID 18502 | — |
| Reactant | HCID 20466347 | HCID 20466347 | — |
| Solvent | Acetonitrile | HCID 6342 | — |
| Product | HCID 13246740 | HCID 13246740 | — |
Reaction Steps
9.3 parts by weight of 3-amino-4-methoxycarbonyl-1,5-dihydrothiophene hydrochloride, 6.0 parts by weight of triethylamine, 7.4 parts by weight of cyclohexyl isocyanate and 30 parts by weight of acetonitrile were combined, and the mixture was stirred for 3 hours at 25° C. and then evaporated down. The residue was washed with water and recrystallized from toluene. 4.5 parts by weight of N-cyclohexyl-N'-(3-methoxycarbonyl-2,5-dihydrothien-4-yl)-urea of melting point 153°-154° C. were obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US04437878 |
|---|
| Source dataset | uspto-grants-1984_03 |
|---|
| ORD ID | ord-7e2f58aac2fc4cb08b3ad2f349293b54 |
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| Source note | uspto-grants-1984_03 |
|---|
