Sodium Hydroxide → HCID 13036292, compound

Participants

Reaction Steps

L-Cysteine hydrochloride monohydrate (20 g), L-malic acid (7.63 g) and sodium hydroxide (4.55 g) are dissolved in water (100 ml), and the mixture is reacted. The resulting aqueous solution is concentrated under reduced pressure until the total amount becomes 57 g, and the solution is allowed to stand at 10° C. overnight. The precipitated crystals are collected by filtration, washed with aqueous isopropyl alcohol and air-dried at 50° C. to give crystalline di-L-cysteine L-malate (14.4 g, yield: 67.2%).

Provenance & Evidence