反应详情

Ten grams (0.035 mol) of 1-(2-cyano-4-hexanoylamino-phenoxy)-2,3-epoxypropane were dissolved in 100 ml of ethanol and, after the addition of 8.3 gm (0.14 mol) of isopropylamine, the mixture was refluxed for one hour. The solvent was evaporated in vacuo, and the remaining residue solidified. It was recrystallized twice from acetonitrile. The white crystalline base was recovered by suction filtration and dried.

1. temperaturethe mixture was refluxed for one hour
2. customThe solvent was evaporated in vacuo
3. customIt was recrystallized twice from acetonitrile
4. filtrationThe white crystalline base was recovered by suction filtration
5. customdried