Benzoyl chloride → HCID 20402882, compound

HRID 1903760Notes

Reaction equation

HRID 1903760 reaction equation
[NH:1]1[C:6]2([CH2:11][CH2:10][CH2:9][CH2:8][CH2:7]2)[CH2:5][CH2:4][CH2:3][CH2:2]1.[C:12](Cl)(=[O:19])[C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1>N1C=CC=CC=1>[C:12]([N:1]1[C:6]2([CH2:11][CH2:10][CH2:9][CH2:8][CH2:7]2)[CH2:5][CH2:4][CH2:3][CH2:2]1)(=[O:19])[C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1

Participants

4

Reactant 2

HCID 7412Benzoyl chlorideHCID 573583HCID 573583, compound

Product 1

HCID 20402882HCID 20402882, compound

Reagents, catalysts & solvents 1

HCID 1049PyridineSolvent

Procedure

The 1-azaspiro[5.5]undecane starting material can be prepared by the method described by H. Hodjat, et al., in J. Heterocyclic Chem., 9, 1081 (1972). This starting material is treated with benzoyl chloride in pyridine to form the N-benzoyl-1-azaspiro-[5.5]undecane, shown at the beginning of step 2.

Sources & evidence

ORD record
ord-389e3b295f164e5dafcf5cb9c57ebe6f
Source dataset
uspto-grants-1984_03
Patent number
US04438130

Reaction notes

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