HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → H-(D)Ala-Gly-OBzl.hydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Diethyl Ether | HCID 3283 | — |
| Reactant | Boc-(D)Ala-Gly-OBzl | HCID 15567200 | — |
| Solvent | 1,4-Dioxane | HCID 31275 | — |
| Product | H-(D)Ala-Gly-OBzl.hydrochloride | HCID 131712174 | — |
Reaction Steps
3.4 g of Boc-(D)Ala-Gly-OBzl are dissolved in 50 ml of dioxane containing HCl and left to stand for one hour. The volume of the solution is reduced under vacuum and an excess of ether added. The precipitated salt is filtered off, dried and used as such for the coupling reaction.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04438103 |
| Source dataset | uspto-grants-1984_03 |
| ORD ID | ord-9f20d9343e204aba90facb8abb9f7130 |
| Source note | uspto-grants-1984_03 |