Oxalic Acid → HCID 20465944, compound

HRID 1904013Notes

Reaction equation

HRID 1904013 reaction equation
[C:1]1([S:7]([NH:10][C:11]2[CH:12]=[C:13]([CH:30]=[CH:31][CH:32]=2)[C:14]([NH:16][CH2:17][CH2:18][S:19][CH2:20][C:21]2[O:22][C:23]([CH2:26][N:27]([CH3:29])[CH3:28])=[CH:24][CH:25]=2)=[O:15])(=[O:9])=[O:8])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[C:33]([OH:38])(=[O:37])[C:34]([OH:36])=[O:35]>C(O)C>[C:33]([OH:38])(=[O:37])[C:34]([OH:36])=[O:35].[C:1]1([S:7]([NH:10][C:11]2[CH:12]=[C:13]([CH:30]=[CH:31][CH:32]=2)[C:14]([NH:16][CH2:17][CH2:18][S:19][CH2:20][C:21]2[O:22][C:23]([CH2:26][N:27]([CH3:29])[CH3:28])=[CH:24][CH:25]=2)=[O:15])(=[O:9])=[O:8])[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=1

Participants

4

Reactant 2

HCID 971Oxalic AcidHCID 13194789HCID 13194789, compound

Product 1

HCID 20465944HCID 20465944, compoundYield 84%

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent2×

Procedure

To a solution of 1 g of 3-benzenesulfonamido-N-[2-(5-dimethylaminomethylfuran-2-ylmethylthio)ethyl]benzamide in 15 ml of ethanol, a solution of 0.3 g of oxalic acid in 10 ml of ethanol is added. The salt which precipitates is filtered, dried and crystallized in 10 ml of 95% ethanol. Thus, 1 g of 3-benzenesulfonamido-N-[2-(5-dimethylaminomethylfuran-2-ylmethylthio)ethyl]benzamide oxalate is obtained as a vitreous solid.

Workup

  1. customThe salt which precipitates
  2. filtrationis filtered
  3. customdried
  4. customcrystallized in 10 ml of 95% ethanol

Sources & evidence

ORD record
ord-2c10054358a14621ab0398e9651e1fc9
Source dataset
uspto-grants-1984_03
Patent number
US04439444

Reaction notes

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