Ethyl 2-(4-nitrophenyl)butanoate → Ethyl 2-(4-aminophenyl)butanoate

HRID 1904020노트

반응식

HRID 1904020 반응식
[N+:1]([C:4]1[CH:9]=[CH:8][C:7]([CH:10]([CH2:16][CH3:17])[C:11]([O:13][CH2:14][CH3:15])=[O:12])=[CH:6][CH:5]=1)([O-])=O>C(O)C.[Pd]>[NH2:1][C:4]1[CH:5]=[CH:6][C:7]([CH:10]([CH2:16][CH3:17])[C:11]([O:13][CH2:14][CH3:15])=[O:12])=[CH:8][CH:9]=1

참가 물질

4

반응물 1

HCID 237528Ethyl 2-(4-nitrophenyl)butanoate

생성물 1

HCID 12692883Ethyl 2-(4-aminophenyl)butanoate수율 94.3%

시약·촉매·용매 2

HCID 23938Palladium촉매HCID 702Ethanol용매

실험 절차

A solution of 9.13 g (0.0385 mole) of ethyl 2-(4-nitrophenyl)-n-butyrate in 150 ml of ethanol was subjected to hydrogenation in the presence of palladium black catalyst to give 7.51 g (0.0363 mole, 94% yield) of ethyl 2-(4-aminophenyl)-n-butyrate.

출처 및 근거

ORD 기록
ord-285fcc7aa4b8467e976b87e80cd03ada
출처 데이터셋
uspto-grants-1984_03
특허 번호
US04439448

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