Potassium Carbonate → HCID 14671822, compound

HRID 1904248Notes

Reaction equation

HRID 1904248 reaction equation
[C:1]([N:5]1[C:10](=[O:11])[C:9]([CH3:12])=[C:8]([OH:13])[CH:7]=[N:6]1)([CH3:4])([CH3:3])[CH3:2].[CH2:14]([O:16][CH2:17][O:18][C:19]1[CH:26]=[CH:25][C:22]([CH2:23]Cl)=[CH:21][CH:20]=1)[CH3:15].C(=O)([O-])[O-].[K+].[K+]>>[C:1]([N:5]1[C:10](=[O:11])[C:9]([CH3:12])=[C:8]([O:13][CH2:23][C:22]2[CH:21]=[CH:20][C:19]([O:18][CH2:17][O:16][CH2:14][CH3:15])=[CH:26][CH:25]=2)[CH:7]=[N:6]1)([CH3:4])([CH3:2])[CH3:3]

Participants

4

Reactant 3

HCID 11430Potassium CarbonateHCID 14671821HCID 14671821, compoundHCID 547131062-tert-Butyl-5-hydroxy-4-methylpyridazin-3(2H)-one

Product 1

HCID 14671822HCID 14671822, compoundYield 57.9%

Procedure

By using 1.0 g of 2-t-butyl-5-hydroxy-4-methyl-3(2H)-pyridazinone, 1.1 g of 4-ethoxymethoxybenzyl chloride and 1.0 g of anhydrous potassium carbonate and similarly to the procedures in Preparation Example 2, 1.1 g of the aimed product was obtained as an oil.

Workup

  1. customsimilarly to the procedures in Preparation Example 2

Sources & evidence

ORD record
ord-9a5726bdfc93488ab3bb929b3f5103c0
Source dataset
uspto-grants-1989_06
Patent number
US04837217

Reaction notes

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