Sodium Hydroxide → HCID 13747175, compound

Participants

Reaction Steps

Ethyl 7-allylamino-1H-pyrazolo[4,3-b]pyridine-6-carboxylate (5.0 g, 20 mmol) was added to a solution of sodium hydroxide (2.4 g, 60 mmol) in water (100 ml) and heated under reflux for 60 min. The solution was filtered, diluted with water (200 ml) and made neutral with 5N hydrochloric acid. The solid was filtered off, washed with water and dried to give the title compound (4.25 g, 96%), m.p. 240°-242° C.

Provenance & Evidence