Ammonia → HCID 70362091, compound

Participants

Reaction Steps

To a solution of ammonia in water (25%) (50 ml) was added 1-methyl-4-ethoxycarbonyl-1,2,5,6-tetrahydropyridinium chloride (Lambrecht & Mutschler, Arzneimittel Forsch. (Drug Res.) 23, 1427 (1973)) (4.5 g; 21,9 mmol) and the mixture was stirred at room temperature for 20 hours. After evaporation in vacuo, the residue was recrystallized from methanol and ether. M.P. 191°-192° C.

Provenance & Evidence