Sodium Hydroxide → HCID 178526458, compound

HRID 1904469Notes

Reaction equation

HRID 1904469 reaction equation
[N+:1]([C:4]1[CH:12]=[C:11]2[C:7]([CH:8]=[N:9][NH:10]2)=[CH:6][CH:5]=1)([O-:3])=[O:2].[OH-].[Na+:14].[Cl:15][O-].[Na+]>>[Na:14][N:10]1[C:11]2[C:7](=[CH:6][CH:5]=[C:4]([N+:1]([O-:3])=[O:2])[CH:12]=2)[C:8]([Cl:15])=[N:9]1

Participants

4

Reactant 3

HCID 14798Sodium HydroxideHCID 242396-NitroindazoleHCID 23665760Sodium Hypochlorite

Product 1

HCID 178526458HCID 178526458, compoundYield 95%

Procedure

To a mixture of 6-nitroindazole (1.63 g) and 6N sodium hydroxide (2.08 ml) was added 5.25% w/v sodium hypochlorite (17.86 ml). After stirring for 30 minutes, filtration, and washing with 1N sodium hydroxide, 1-sodio-3-chloro-6-nitroindazole (2.08 g, 95%) was obtained as a solid; mp >270° C.

Workup

  1. additionwas added 5.25%
  2. filtrationfiltration
  3. washwashing with 1N sodium hydroxide

Sources & evidence

ORD record
ord-bf33b6b4b62e4751b48992ccad28cc7e
Source dataset
uspto-grants-1989_06
Patent number
US04837235

Reaction notes

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