Methyl p-toluenesulfonate → HCID 20039290, compound

HRID 1904506Notes

Reaction equation

HRID 1904506 reaction equation
[F:1][C:2]([F:31])([F:30])[C:3]1[CH:4]=[C:5]([P:9]([C:20]2[CH:25]=[CH:24][CH:23]=[C:22]([C:26]([F:29])([F:28])[F:27])[CH:21]=2)[C:10]2[CH:15]=[CH:14][CH:13]=[C:12]([C:16]([F:19])([F:18])[F:17])[CH:11]=2)[CH:6]=[CH:7][CH:8]=1.[S:32]([C:37]1[CH:43]=[CH:42][C:40]([CH3:41])=[CH:39][CH:38]=1)([O:35][CH3:36])(=[O:34])=[O:33]>>[S:32]([C:37]1[CH:43]=[CH:42][C:40]([CH3:41])=[CH:39][CH:38]=1)([O-:35])(=[O:34])=[O:33].[CH3:36][P+:9]([C:5]1[CH:6]=[CH:7][CH:8]=[C:3]([C:2]([F:1])([F:30])[F:31])[CH:4]=1)([C:20]1[CH:25]=[CH:24][CH:23]=[C:22]([C:26]([F:29])([F:27])[F:28])[CH:21]=1)[C:10]1[CH:15]=[CH:14][CH:13]=[C:12]([C:16]([F:18])([F:19])[F:17])[CH:11]=1

Participants

3

Reactant 2

HCID 6645Methyl p-toluenesulfonateHCID 427977Phosphine, tris[3-(trifluoromethyl)phenyl]-

Product 1

HCID 20039290HCID 20039290, compoundYield 88%

Procedure

A mixture of 6.20 g (13.3 mmol) of tris(3-trifluoromethylphenyl)phosphine and 2.94 g (15.8 mmol) of methyl tosylate were allowed to react for 3 hr at 140° C. A total of 7.64 g (11.7 mmol, 88.0 %) of product was obtained, which was further purified by recrystallization from toluene-ethanol.

Workup

  1. customto react for 3 hr at 140° C

Sources & evidence

ORD record
ord-b1e59d59f530498c842612bb54e4f159
Source dataset
uspto-grants-1989_06
Patent number
US04837391

Reaction notes

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