Methyl p-toluenesulfonate → HCID 20039305, compound

HRID 1904507Notes

Reaction equation

HRID 1904507 reaction equation
[F:1][C:2]([F:31])([F:30])[C:3]1[CH:8]=[CH:7][C:6]([P:9]([C:20]2[CH:25]=[CH:24][C:23]([C:26]([F:29])([F:28])[F:27])=[CH:22][CH:21]=2)[C:10]2[CH:15]=[CH:14][C:13]([C:16]([F:19])([F:18])[F:17])=[CH:12][CH:11]=2)=[CH:5][CH:4]=1.[S:32]([C:37]1[CH:43]=[CH:42][C:40]([CH3:41])=[CH:39][CH:38]=1)([O:35][CH3:36])(=[O:34])=[O:33]>>[S:32]([C:37]1[CH:43]=[CH:42][C:40]([CH3:41])=[CH:39][CH:38]=1)([O-:35])(=[O:34])=[O:33].[CH3:36][P+:9]([C:6]1[CH:5]=[CH:4][C:3]([C:2]([F:1])([F:30])[F:31])=[CH:8][CH:7]=1)([C:20]1[CH:25]=[CH:24][C:23]([C:26]([F:29])([F:27])[F:28])=[CH:22][CH:21]=1)[C:10]1[CH:15]=[CH:14][C:13]([C:16]([F:18])([F:19])[F:17])=[CH:12][CH:11]=1

Participants

3

Reactant 2

HCID 6645Methyl p-toluenesulfonateHCID 139448Tris(4-trifluoromethylphenyl)phosphine

Product 1

HCID 20039305HCID 20039305, compoundYield 73.4%

Procedure

A mixture of 5.25 g (11.3 mmol) of tris (4-trifluoromethylphenyl)phosphine and 2.43 g (13.0 mmol) of methyl tosylate were allowed to react for 2 hr at 135° C. A total of 5.41 g (8.29 mmol, 73.4%) of product was obtained, which was further purified by recrystallization from toluene-ethanol.

Workup

  1. customto react for 2 hr at 135° C

Sources & evidence

ORD record
ord-9012b5c2a79944cc8e88d19752d17fda
Source dataset
uspto-grants-1989_06
Patent number
US04837391

Reaction notes

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