Pyrogallol → Bendiocarb phenol

HRID 1904551Notes

Reaction equation

HRID 1904551 reaction equation
[C:1]1([CH:9]=[CH:8][CH:7]=[C:5]([OH:6])[C:3]=1[OH:4])[OH:2].CO[C:12](OC)([CH3:14])[CH3:13]>C1(C)C=CC=CC=1>[CH3:13][C:12]1([CH3:14])[O:2][C:1]2[CH:9]=[CH:8][CH:7]=[C:5]([OH:6])[C:3]=2[O:4]1

Participants

4

Reactant 2

HCID 1057PyrogallolHCID 64952,2-Dimethoxypropane

Product 1

HCID 62765Bendiocarb phenolYield 17%

Reagents, catalysts & solvents 1

HCID 1140TolueneSolvent

Procedure

A mixture of 9.0 g of pyrogallol, 7.5 g of 2,2-dimethoxypropane and 100 ml of toluene was refluxed for 4.5 hours. After cooling, the reaction mixture was worked up in a customary manner and purified by column chromatography to give 2.0 g (yield 17%) of the desired product as a pale yellow solid.

Workup

  1. temperaturewas refluxed for 4.5 hours
  2. temperatureAfter cooling
  3. custompurified by column chromatography

Sources & evidence

ORD record
ord-ed9810360aaa466899de3ea20b2b4326
Source dataset
uspto-grants-1989_06
Patent number
US04838924

Reaction notes

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