Potassium Carbonate → HCID 54355794, compound

HRID 1904607Notes

Reaction equation

[Br:1][C:2]1[C:21](F)=[CH:20][C:5]([C:6]([C:8](=[CH:14][NH:15][C@H:16](C)[CH2:17][OH:18])[C:9]([O:11][CH2:12][CH3:13])=[O:10])=[O:7])=[C:4](F)[C:3]=1[F:24].[C:25](=O)([O-])[O-].[K+].[K+]>>[Br:1][C:2]1[C:3]([F:24])=[CH:4][C:5]2[C:6](=[O:7])[C:8]([C:9]([O:11][CH2:12][CH3:13])=[O:10])=[CH:14][N:15]3[CH2:16][C@@H:17]([CH3:25])[O:18][C:21]=1[C:20]=23

Participants

Reactant 2

HCID 11430Potassium Carbonate

HCID 178472050HCID 178472050, compound

Product 1

HCID 54355794HCID 54355794, compound

Procedure

[II; R=C2H5, R'=H, R"=CH3 ] was prepared by cyclization of the compound of part (c) above with potassium carbonate according to the procedure of Example 1(c). The crude product was used directly in the next reaction.

Sources & evidence

ORD record: ord-26540ab96caa42fcbaaa760edeb4437a
Source dataset: uspto-grants-1989_06
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04839355

Reaction notes

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