Isatin → Acetylisatin

HRID 1904611Notes

Reaction equation

[NH:1]1[C:11]2[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=2)[C:4](=[O:5])[C:2]1=[O:3].C1(C)C=CC=CC=1.[CH3:19][CH2:20][O:21]C(C)=O>>[C:20]([N:1]1[C:11]2[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=2)[C:4](=[O:5])[C:2]1=[O:3])(=[O:21])[CH3:19]

Participants

Reactant 2

HCID 7054Isatin

HCID 21584019Toluene ethylacetate

Product 1

HCID 11321Acetylisatin

Procedure

T.L.C. (PhCH3 /AcOEt=75/25): slightly impure for isatin.

Sources & evidence

ORD record: ord-08742313f1294a119efab781ae3d6d32
Source dataset: uspto-grants-1989_06
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04839366

Reaction notes

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