Ethyl bromoacetate → HCID 20037770, compound

HRID 1904672Notes

Reaction equation

HRID 1904672 reaction equation
[Na].[N:2]1[C:11]2[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=2)[CH:5]=[CH:4][C:3]=1[CH2:12][O:13][C:14]1[CH:15]=[C:16]([C:20]2[NH:24][N:23]=[N:22][N:21]=2)[CH:17]=[CH:18][CH:19]=1.[CH2:25]([O:27][C:28](=[O:31])[CH2:29]Br)[CH3:26]>C(O)C>[C:28]([CH2:29][N:22]1[N:23]=[N:24][C:20]([C:16]2[CH:17]=[CH:18][CH:19]=[C:14]([O:13][CH2:12][C:3]3[CH:4]=[CH:5][C:6]4[C:11](=[CH:10][CH:9]=[CH:8][CH:7]=4)[N:2]=3)[CH:15]=2)=[N:21]1)([O:27][CH2:25][CH3:26])=[O:31]

Participants

5

Reactant 3

HCID 7748Ethyl bromoacetateHCID 5360545SodiumHCID 178420706HCID 178420706, compound

Product 1

HCID 20037770HCID 20037770, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

To a solution of 0.2 g sodium in 30 ml ethanol was first added 1.1 g of 5-[3-(2-quinolylmethyloxy)phenyl]tetrazole and then 30 minutes 0.6 g of ethylbromoacetate and stirring was continued at 80° C. for 16 hours.

Sources & evidence

ORD record
ord-4a21c923e9694d84b322ab1bb9880502
Source dataset
uspto-grants-1989_06
Patent number
US04839369

Reaction notes

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