HCID 13935150, compound → HCID 14253843, compound

HRID 1904745Notes

Reaction equation

HRID 1904745 reaction equation
[CH2:1]([O:8][C:9]1[CH:31]=[CH:30][C:12]([CH2:13][NH:14][C:15]2[C:16]3[C:21]([N:22]=[C:23]4[C:28]=2[C:27](=[O:29])[CH2:26][CH2:25][CH2:24]4)=[CH:20][CH:19]=[CH:18][CH:17]=3)=[CH:11][CH:10]=1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[H-].[Al+3].[Li+].[H-].[H-].[H-]>O1CCCC1>[CH2:1]([O:8][C:9]1[CH:10]=[CH:11][C:12]([CH2:13][NH:14][C:15]2[C:16]3[C:21]([N:22]=[C:23]4[C:28]=2[CH:27]([OH:29])[CH2:26][CH2:25][CH2:24]4)=[CH:20][CH:19]=[CH:18][CH:17]=3)=[CH:30][CH:31]=1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

Participants

4

Reactant 2

HCID 13935150HCID 13935150, compoundHCID 21226445Aluminium lithium hydride

Product 1

HCID 14253843HCID 14253843, compound

Reagents, catalysts & solvents 1

HCID 8028TetrahydrofuranSolvent2×

Procedure

To a cooled suspension of 4.75 g of 3,4-dihydro-9-[4-(benzyloxy)benzylamino]acridin-1(2H)-one in 75 ml of tetrahydrofuran was added 6 ml of 1M solution of lithium aluminum hydride in tetrahydrofuran. This was stirred for 1 hour.

Sources & evidence

ORD record
ord-ad644ca5fa6c4aee9a90b7ba294e3948
Source dataset
uspto-grants-1989_06
Patent number
US04839364

Reaction notes

Loading…