HuagongsheHuagongshe Chemistry Print Report · For research reference only
Thiourea → HCID 178505786, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Thiourea | HCID 2723790 | — |
| Reactant | 1-(4-Fluorobenzyl)-2-chlorobenzimidazole | HCID 3020241 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 178505786 | HCID 178505786 | — |
Reaction Steps
A mixture of 8.35 parts of thiourea, 26 parts of 2-chloro-1-[(4-fluorophenyl)methyl]-1H-benzimidazole and 400 parts of ethanol was stirred and refluxed for 5 hours. The reaction mixture was evaporated. The residue was suspended in 2,2'-oxybispropane. The precipitated product was filtered off and crystallized from ethanol, yielding 6.1 parts of 1-[(4-fluorophenyl)methyl]-1H-benzimidazole-2-thiol; mp. 194.7° C. (62).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04839374 |
| Source dataset | uspto-grants-1989_06 |
| ORD ID | ord-6d5e22122714489ab2c19ed8cb663bfd |
| Source note | uspto-grants-1989_06 |