反应详情

In 100 of ethyl acetate was dissolved 15 g (57×10-3 mole) of 2-benzamido-4-chloro-5-aminophenol, and then 21 g of 2-(2,4-di-t-amylphenoxy)butanoic acid chloride and 5 g of pyridine were added thereto and the mixture was stirred at room temperature for 3 hours. After the reaction, a solvent was distilled off, and the residue was separated and purified through column chromatography and recrystallized from n-hexane to obtain the title compound. Yield: 14.1 g, FD-Mass: 564, melting point: 190° to 191° C.

1. customAfter the reaction
2. distillationa solvent was distilled off
3. customthe residue was separated
4. custompurified through column chromatography
5. customrecrystallized from n-hexane