反应详情

In 100 ml of acetic acid and 100 ml of dimethylformamide was dissolved 20 g (35×10-3 mole) of 2-benzamido-4-chloro-5-{2-(2,4-di-t-amylphenoxy)butanamido}phenol. To the solution was added dropwise slowly a solution of 2.7 g of sodium nitrite dissolved in 5 ml of a distilled water at room temperature, and then the mixture was stirred for 2 hours. The reaction mixture was poured into ice-cold water, and precipitated yellow solids were collected by filtration and washed with water. Yield: 21 g.

1. additionThe reaction mixture was poured into ice-cold water
2. customprecipitated yellow solids
3. filtrationwere collected by filtration
4. washwashed with water