Cysteine Hydrochloride → HCID 57041611, compound

HRID 1904901Notes

Reaction equation

HRID 1904901 reaction equation
[CH3:1][O:2][C:3]1[CH:4]=[C:5]2[C:10](=[CH:11][CH:12]=1)[CH:9]=[C:8]([C@H:13]([CH3:16])[CH:14]=O)[CH:7]=[CH:6]2.Cl.[NH2:18][C@H:19]([C:22]([OH:24])=[O:23])[CH2:20][SH:21].C([O-])(=O)C.[K+]>CC(C)=O.O>[CH3:1][O:2][C:3]1[CH:4]=[C:5]2[C:10](=[CH:11][CH:12]=1)[CH:9]=[C:8]([C@@H:13]([CH:14]1[NH:18][C@H:19]([C:22]([OH:24])=[O:23])[CH2:20][S:21]1)[CH3:16])[CH:7]=[CH:6]2

Participants

6

Reactant 3

HCID 60960Cysteine HydrochlorideHCID 517044Potassium AcetateHCID 1183081032305-59-2

Product 1

HCID 57041611HCID 57041611, compound

Reagents, catalysts & solvents 2

HCID 180AcetoneSolvent2×HCID 962WaterSolvent

Procedure

A solution of (2S)-2-(6-methoxy-2-napthyl)-propanal (8.2 g; 38.3 mmoles) in acetone (50 ml) is added dropwise to a solution of (R)-cysteine hydrochloride (5.94 g; 37.6 mmoles) and of potassium acetate (3.69 g; 37.6 mmoles) in 100 ml of water and acetone (1:1 v/v) kept under stirring at room temperature.

Sources & evidence

ORD record
ord-1b7cd935eb62427fa7ca27c96274587b
Source dataset
uspto-grants-1989_06
Patent number
US04840936

Reaction notes

Loading…