Perchloric Acid → HCID 20036619, compound

HRID 1904986Notes

Reaction equation

HRID 1904986 reaction equation
Cl(O)(=O)(=O)=O.C[O:7][CH:8]=[C:9]([C:14]1[CH:19]=[CH:18][C:17]([C:20]([F:23])([F:22])[F:21])=[CH:16][CH:15]=1)[C:10]([F:13])([F:12])[F:11]>C(OCC)C>[F:21][C:20]([F:22])([F:23])[C:17]1[CH:18]=[CH:19][C:14]([CH:9]([C:10]([F:13])([F:12])[F:11])[CH:8]=[O:7])=[CH:15][CH:16]=1

Participants

4

Reactant 2

HCID 24247Perchloric AcidHCID 538386822-(4-Trifluoromethylphenyl)-3,3,3-trifluoropropenyl methyl ether

Product 1

HCID 20036619HCID 20036619, compoundYield 36.3%

Reagents, catalysts & solvents 1

HCID 3283Diethyl EtherSolvent

Procedure

Under a nitrogen atmosphere, 10 ml of 70% perchloric acid was added to a solution of 6.1 g of 2-(4-trifluoromethylphenyl)-3,3,3-trifluoropropenyl methyl ether in 20 ml of diethyl ether at 0° to 5° C. The reaction solution was stirred at room temperature for 14 hours. The reaction mixture was poured into ice water and extracted twice with diethyl ether. The ether layers were combined and washed with saturated sodium bisulfate solution and saturated sodium chloride solution successively and dried over anhydrous magnesium sulfate. The solvent was removed under reduced pressure to obtain 2.1 g of the desired crude compound.

Workup

  1. extractionextracted twice with diethyl ether
  2. washwashed with saturated sodium bisulfate solution and saturated sodium chloride solution successively
  3. dry with materialdried over anhydrous magnesium sulfate
  4. customThe solvent was removed under reduced pressure

Sources & evidence

ORD record
ord-e1d692449b2447c1b174c967d3284c11
Source dataset
uspto-grants-1989_06
Patent number
US04840971

Reaction notes

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