Methylamine → HCID 15598737, compound

HRID 1905057Notes

Reaction equation

HRID 1905057 reaction equation
[OH:1][C:2]1[CH:25]=[CH:24][C:5]([C:6]2[C:15](=[O:16])[C:14]3[C:9](=[CH:10][C:11]([OH:18])=[CH:12][C:13]=3[OH:17])[O:8][C:7]=2[C:19](OCC)=[O:20])=[CH:4][CH:3]=1.[CH3:26][NH2:27]>>[OH:1][C:2]1[CH:25]=[CH:24][C:5]([C:6]2[C:15](=[O:16])[C:14]3[C:9](=[CH:10][C:11]([OH:18])=[CH:12][C:13]=3[OH:17])[O:8][C:7]=2[C:19]([NH:27][CH3:26])=[O:20])=[CH:4][CH:3]=1

Participants

3

Reactant 2

HCID 6329MethylamineHCID 14459364HCID 14459364, compound

Product 1

HCID 15598737HCID 15598737, compound

Procedure

A mixture of ethyl 4',5,7-trihydroxy-2-isoflavonecarboxylate (100 mg) and 30% methanolic solution of methylamine (5 ml) was stirred at room temperature for 30 minutes, the solvent was distilled off under reduced pressure, and the solid residue was recrystallized from methanol, affording 50 mg of 4',5,7-trihydroxy-N-methyl-2-isoflavonecarboxamide.

Workup

  1. distillationthe solvent was distilled off under reduced pressure
  2. customthe solid residue was recrystallized from methanol

Sources & evidence

ORD record
ord-a1baa92b3b9346d5a5ba2640db54a02f
Source dataset
uspto-grants-1989_06
Patent number
US04841077

Reaction notes

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