反应详情

Hydrogen chloride was passed into a solution of 110 mg of (2RS, 3S)-3-amino-2-hydroxy-5-methylhexanoic acid in 10 ml of methanol under ice-cooling, and the mixture was stirred overnight. The reaction mixture was evaporated under reduced pressure to obtained 150 mg of methyl (2RS, 3S)-3-amino-2-hydroxy-5-methyl-hexanoate hydrochloride as a white powder [IR (KBr): νco 1740 cm-1 ].

1. temperaturecooling
2. customThe reaction mixture was evaporated under reduced pressure