HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ammonia → 2-Aminoadenosine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ammonia | HCID 222 | — |
| Reactant | 2-amino-6-chloro-9-(2,3,5-O-triacetyl-beta-D-ribofuranosyl)-9H-purine | HCID 86743189 | — |
| Product | 2-Aminoadenosine | HCID 72200 | — |
Reaction Steps
The 6-position of 2-amino-6-chloro-9-(2,3,5-O-triacetyl-β-D-ribofuranosyl)-9H-purine was aminated by ammonia to give 2-aminoadenosine. In the same manner as Example 1 [METHOD 1], 2-aminoadenosine was methylated to give 2-amino-2'-O-methyladenosine (Compound 30) and 2-amino-3'-O-methyladenosine (Compound 31).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04843066 |
| Source dataset | uspto-grants-1989_06 |
| ORD ID | ord-876254ec4b6c46bb8e0f57ae3efdafc8 |
| Source note | uspto-grants-1989_06 |