Triphenylphosphine → 3-(5-Bromopentyl)-5-methylisoxazole

HRID 1905485Notes

Reaction equation

HRID 1905485 reaction equation
[Br:1]Br.C1(P([C:16]2[CH:21]=CC=CC=2)C2C=CC=CC=2)C=CC=CC=1.[CH3:22][C:23]1[O:27][N:26]=[C:25]([CH2:28][CH2:29][CH2:30]Br)[CH:24]=1>>[Br:1][CH2:21][CH2:16][CH2:30][CH2:29][CH2:28][C:25]1[CH:24]=[C:23]([CH3:22])[O:27][N:26]=1

Participants

4

Reactant 3

HCID 11776TriphenylphosphineHCID 24408BromineHCID 133169753-(3-Bromopropyl)-5-methyl-1,2-oxazole

Product 1

HCID 133169783-(5-Bromopentyl)-5-methylisoxazoleYield 77%

Procedure

3-(5-Bromopentyl)-5-methylisoxazole [XXVII; R9 =CH3, Hal=Br] was prepared by reacting 3-(5-hydroxpentyl)-5-methylisoxazole with bromine and triphenylphosphine according to the procedure of part (f) above, and was obtained in 77% yield as an oil, b.p. 140°-150° C.(0.05 mm).

Workup

  1. customwas obtained in 77% yield as an oil, b.p. 140°-150° C.(0.05 mm)

Sources & evidence

ORD record
ord-325d9fde7e9f4384bd337c4cb3fc0445
Source dataset
uspto-grants-1989_06
Patent number
US04843087

Reaction notes

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