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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1905549Generated: October 26, 2026

Ammonia → 4-(2-Aminopropan-2-yl)phenol

https://huagongshe.com/reaction/1905549

Reaction equation

Participants

RoleNameHCIDCharge
ReactantAmmoniaHCID 222—
Reactantp-IsopropenylphenolHCID 584247—
Product4-(2-Aminopropan-2-yl)phenolHCID 14178126—

Reaction Steps

A 0.10-g sample of 4-(1-methylethenyl)phenol is exposed to excess, gaseous ammonia for about one day at 50° C. After excess ammonia is purged, a quantitative yield of 2-amino-2-(4-hydroxyphenyl)propane is obtained. No 1-amino-2-(4-hydroxyphenyl)propane is detectable by 60 MHz proton NMR.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04843160
Source datasetuspto-grants-1989_06
ORD IDord-e169062d2a044d4e89161f26aad11c43
Source noteuspto-grants-1989_06