HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 136134531, compound → HCID 135782143, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 136134531 | HCID 136134531 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 135782143 | HCID 135782143 | — |
Reaction Steps
6.0 g (0.016 mole) of 5-methyl-1'-benzyloxycarbonyl-spiro-[1H-1,4-benzodiazepine-3,4'-piperidin]-2(3H)-one are hydrogenated in 250 ml of ethanol in the presence of 0.5 g of palladium-on-charcoal at 20° C. After the catalyst has been removed by filtration, the filtrate is concentrated and, after addition of diethyl ether, the residue crystallizes.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04647560 |
| Source dataset | uspto-grants-1987_03 |
| ORD ID | ord-742114cccd304b35927c20b4cd046fd5 |
| Source note | uspto-grants-1987_03 |