3,5-Dichloroaniline → 2,3,5-Trichloroaniline

HRID 1905821Notes

Reaction equation

HRID 1905821 reaction equation
[Cl:1][C:2]1[C:8]([Cl:9])=[C:7](Cl)[C:6]([Cl:11])=[CH:5][C:3]=1[NH2:4].ClC1C=C(C=C(Cl)C=1)N>>[Cl:1][C:2]1[C:8]([Cl:9])=[CH:7][C:6]([Cl:11])=[CH:5][C:3]=1[NH2:4]

Participants

3

Reactant 2

HCID 122813,5-DichloroanilineHCID 124662,3,4,5-Tetrachloroaniline

Product 1

HCID 876762,3,5-TrichloroanilineYield 37.5%

Procedure

Under these conditions, it is observed that the degree of conversion (DC) of the 2,3,4,5-tetrachloroaniline is 99.5% and the actual yield of 3,5-dichloroaniline is 61.1%; 37.5% of 2,3,5-trichloroaniline, formed as an intermediate, remains.

Sources & evidence

ORD record
ord-b15c6743e57044db9585d48005aeffc1
Source dataset
uspto-grants-1987_03
Patent number
US04647700

Reaction notes

Loading…