反应详情

To a solution of 3,4-dihydro-1,3-dimethyl-6-(4-hydroxy-3-methoxyphenyl)-4-(2,4,6-trimethylphenylimino)-2(1H)-pyrimidinone (0.40 g) in acetone (20 ml) were added potassium carbonate (0.16 g) and ethyl bromoacetate (0.66 ml), and the mixture was refluxed for 10 hours. After being cooled, the mixture was evaporated and suspended in chloroform. The suspension was washed with water, dried over sodium sulfate, and evaporated to give crude oil of 3,4-dihydro-1,3-dimethyl-6-(4-ethoxycarbonylmethoxy-3-methoxyphenyl)-4-(2,4,6-trimethylphenylimino)-2(1H)-pyrimidinone (0.67 g). This crude oil was used for the following deesterification without further purification.

1. temperaturethe mixture was refluxed for 10 hours
2. temperatureAfter being cooled
3. customthe mixture was evaporated
4. washThe suspension was washed with water
5. dry with materialdried over sodium sulfate
6. customevaporated