反应详情

2-Mercapto-4-(4-nitro-phenyl)-1H-imidazole (21.1 g) was added in portions to a solution of sodium (2.3 g) in ethanol (190 ml). After 15 minutes of stirring, a solution of iodomethane (14.2 g) in ethanol (50 ml) was added dropwise. After an additional 2 hours of stirring at room temperature, the solution was evaporated to dryness. The residual solid was treated with water, filtered off and dried to give 18.1 g of the title compound.

1. stirringAfter an additional 2 hours of stirring at room temperature
2. customthe solution was evaporated to dryness
3. additionThe residual solid was treated with water
4. filtrationfiltered off
5. customdried