反应详情

温度

60 °C

Hydrogen peroxide (36%, 100 ml) was added over a period of 2 hours, while stirring, to a hot (60° C.) solution of 2-methylthio-4-(4-nitro-phenyl)-1H-imidazole (19.6 g) in methanol (500 ml). After an additional 24 hours of heating at 60° C., the mixture was cooled to room temperature, filtered, and the filter cake was dried to give 16.1 g of the title compound.

1. temperaturethe mixture was cooled to room temperature
2. filtrationfiltered
3. customthe filter cake was dried