Hydrogen Peroxide → HCID 178504615, compound

HRID 1905936Notes

Reaction equation

HRID 1905936 reaction equation
[OH:1]O.[CH3:3][S:4][C:5]1[NH:6][CH:7]=[C:8]([C:10]2[CH:15]=[CH:14][C:13]([N+:16]([O-:18])=[O:17])=[CH:12][CH:11]=2)[N:9]=1>CO>[CH3:3][S:4]([C:5]1[NH:6][CH:7]=[C:8]([C:10]2[CH:11]=[CH:12][C:13]([N+:16]([O-:18])=[O:17])=[CH:14][CH:15]=2)[N:9]=1)=[O:1]

Participants

4

Reactant 2

HCID 784Hydrogen PeroxideHCID 178503389HCID 178503389, compound

Product 1

HCID 178504615HCID 178504615, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Conditions

Temperature
60 °C

Procedure

Hydrogen peroxide (36%, 100 ml) was added over a period of 2 hours, while stirring, to a hot (60° C.) solution of 2-methylthio-4-(4-nitro-phenyl)-1H-imidazole (19.6 g) in methanol (500 ml). After an additional 24 hours of heating at 60° C., the mixture was cooled to room temperature, filtered, and the filter cake was dried to give 16.1 g of the title compound.

Workup

  1. temperaturethe mixture was cooled to room temperature
  2. filtrationfiltered
  3. customthe filter cake was dried

Sources & evidence

ORD record
ord-45884a17712344ee8d59d2cfcbfc90f0
Source dataset
uspto-grants-1987_03
Patent number
US04649150

Reaction notes

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