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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1905965Generated: October 30, 2026

Chloroacetic Acid → 2-[2-(4-Fluorophenyl)ethoxy]acetic acid

https://huagongshe.com/reaction/1905965

Reaction equation

Participants

RoleNameHCIDCharge
ReactantChloroacetic AcidHCID 300—
ReactantMethylcyclohexaneHCID 7962—
Reactant4-Fluorophenethyl AlcoholHCID 82068—
Product2-[2-(4-Fluorophenyl)ethoxy]acetic acidHCID 1320892379%

Reaction Steps

7.0 g of 4-fluorophenethyl alcohol were reacted with 4.73 g of chloroacetic acid in a manner analogous to that described in Example 1(a) to give 7.8 g (79%) of 2-(4-fluorophenyl)ethoxyacetic acid of melting point 82°-85° C. (from methylcyclohexane).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04649160
Source datasetuspto-grants-1987_03
ORD IDord-391d245eecff439ab3cf621b91567243
Source noteuspto-grants-1987_03