HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl Acetate → 4-(2-Phenethyloxyethoxy)phenol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl Acetate | HCID 8857 | — |
| Reactant | 1-Benzyloxy-4-(2-phenethyloxyethoxy)benzene | HCID 20213727 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 4-(2-Phenethyloxyethoxy)phenol | HCID 20213720 | 91% |
Reaction Steps
The 1-benzyloxy-4-(2-phenethyloxyethoxy)benzene obtained according to the preceding paragraph was dissolved in 200 ml of ethanol and 200 ml of ethyl acetate and hydrogenated overnight at atmospheric pressure and room temperature in the presence of 0.4 g of 10% palladium/carbon. The catalyst was removed by filtration and the filtrate was evaporated to give 10.8 g (91%) of 4-(2-phenethyloxyethoxy)phenol in the form of an oil which was homogeneous according to chromatography.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04649160 |
| Source dataset | uspto-grants-1987_03 |
| ORD ID | ord-0e006ecf2e0540c9b023e26ed794f5cc |
| Source note | uspto-grants-1987_03 |