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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1905980Generated: November 1, 2026

Chloroacetic Acid → 2-(4-Chlorophenyl)ethoxyacetic acid

https://huagongshe.com/reaction/1905980

Reaction equation

Participants

RoleNameHCIDCharge
ReactantChloroacetic AcidHCID 300—
Reactantp-Chlorophenethylic alcoholHCID 74647—
SolventEthyl acetate hexaneHCID 21226206—
Product2-(4-Chlorophenyl)ethoxyacetic acidHCID 13208925105.4%

Reaction Steps

3.15 g of 4-chlorophenethyl alcohol were reacted with 2.2 g of chloroacetic acid in a manner analogous to that described in Example 1(a) to give 4.55 g (91%) of 2-(4-chlorophenyl)ethoxyacetic acid of melting point 75°-77° C. (from ethyl acetate/hexane).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04649160
Source datasetuspto-grants-1987_03
ORD IDord-f34e4f5159a84048b234e615cf405b11
Source noteuspto-grants-1987_03