Hydrochloric Acid → HCID 20145067, compound

HRID 1906022Notes

Reaction equation

HRID 1906022 reaction equation
[CH3:1][NH:2][C:3]1[S:4][C:5]([C:9]2[S:13][C:12]([NH:14][CH3:15])=[N:11][C:10]=2[CH3:16])=[C:6]([CH3:8])[N:7]=1.[ClH:17]>C(O)C>[ClH:17].[ClH:17].[CH3:1][NH:2][C:3]1[S:4][C:5]([C:9]2[S:13][C:12]([NH:14][CH3:15])=[N:11][C:10]=2[CH3:16])=[C:6]([CH3:8])[N:7]=1

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 15505523HCID 15505523, compound

Product 1

HCID 20145067HCID 20145067, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

To a suspension of 2,2'-dimethylamino-4,4'-dimethyl-5,5'-bithiazole (1.9 g) in ethanol (100 ml) was added conc. hydrochloric acid (2 ml) and the resulting solution was evaporated in vacuo. The residue was dissolved in ethanol (100 ml) and the solution was concentrated in vacuo. The resulting precipitate was collected by filtration and washed with diethyl ether to give 2,2'-dimethylamino-4,4'-dimethyl-5,5'-bithiazole dihydrochloride (1.86 g). mp 277° C. (dec.)

Workup

  1. customthe resulting solution was evaporated in vacuo
  2. dissolutionThe residue was dissolved in ethanol (100 ml)
  3. concentrationthe solution was concentrated in vacuo
  4. filtrationThe resulting precipitate was collected by filtration
  5. washwashed with diethyl ether

Sources & evidence

ORD record
ord-ccbaf8fb60504e11b375d0d7c42ac10b
Source dataset
uspto-grants-1987_03
Patent number
US04649146

Reaction notes

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