2-Methylglycerol tetrahydropyranyl ether → 3-(2-Hydroxyoctadecyloxy)-2-methoxypropyl tetrahydropyranyl ether

HRID 1906052Notes

Reaction equation

HRID 1906052 reaction equation
[O:1]1[C:3]([CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH3:19])=[CH:2]1.[O:20]1[CH2:25][CH2:24][CH2:23][CH2:22][CH:21]1[O:26][CH2:27][CH:28]([CH2:31][OH:32])[O:29][CH3:30]>>[O:20]1[CH2:25][CH2:24][CH2:23][CH2:22][CH:21]1[O:26][CH2:27][CH:28]([O:29][CH3:30])[CH2:31][O:32][CH2:2][CH:3]([OH:1])[CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH3:19]

Participants

3

Reactant 2

HCID 135630772-Methylglycerol tetrahydropyranyl etherHCID 202138261,2-Epoxyoctadecene

Product 1

HCID 202138243-(2-Hydroxyoctadecyloxy)-2-methoxypropyl tetrahydropyranyl etherYield 55%

Procedure

The above 1,2-epoxyoctadecane (23) (5.5 g, 20.5 mmoles) was reacted with 7.8 g (41 mmoles) of 2-methylglycerol monotetrahydropyranyl ether in the same manner as Example 1-2 to give 5.1 g (55%) of the desired compound (24) as a colorless wax.

Sources & evidence

ORD record
ord-72c28bc35aff4faaa6c01c8dc43e3823
Source dataset
uspto-grants-1987_03
Patent number
US04649203

Reaction notes

Loading…