Water → HCID 20213009, compound

Participants

Reaction Conditions

Reaction Steps

A suspension of 5.0 g of 6-chloro-2-hydrazinopyridine-4-carbonitrile in 50 ml of pyridine was cooled to 0° C. in an ice bath and 3.1 g of acetyl chloride was added dropwise over a 10 minute period. The mixture became homogeneous after the addition and it was allowed to warm to ambient temperature. After 2 hours, the reaction mixture was poured into 180 ml of water and the precipitate which formed was separated by filtration and dried to give N-acetyl-N'-(6-chloro-4-cyano-2-pyridyl)hydrazine which was purified by recrystallization from ethanol.

Provenance & Evidence