Acetone → 2-(1-(Triisopropylsilyl)-1H-pyrrolo[2,3-b]pyridin-5-yl)propan-2-ol
Reaction equation
[Br:1][c:2]1[cH:3][c:4]2[c:5]([n:6][cH:7]1)[n:8]([Si:11]([CH:12]([CH3:13])[CH3:14])([CH:15]([CH3:16])[CH3:17])[CH:18]([CH3:19])[CH3:20])[cH:9][cH:10]2.[C:21]([Li:22])([CH3:23])([CH3:24])[CH3:25].[CH3:26][C:27]([CH3:28])=[O:29].[O:31]1[CH2:32][CH2:33][CH2:34][CH2:35]1.[OH2:30]>>[c:2]1([C:27]([CH3:26])([CH3:28])[OH:29])[cH:3][c:4]2[c:5]([n:6][cH:7]1)[n:8]([Si:11]([CH:12]([CH3:13])[CH3:14])([CH:15]([CH3:16])[CH3:17])[CH:18]([CH3:19])[CH3:20])[cH:9][cH:10]2Participants
6
Sources & evidence
- ORD record
- ord-1b083262a9de46ca8fff41b06c798a93
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
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